CN
- Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
Journal of inorganic biochemistry (2011-03-23)
Lee Fang Chin, Siew Ming Kong, Hoi Ling Seng, Kong Soo Khoo, Rajamurthy Vikneswaran, Siang Guan Teoh, Munirah Ahmad, Soo Beng Alan Khoo, Mohd Jamil Maah, Chew Hee Ng
PMID21421121
摘要
The synthesis and characterization of two cobalt(II) complexes, Co(phen)(ma)Cl 1 and Co(ma)(2)(phen) 2, (phen=1,10-phenanthroline, ma(-)=maltolate or 2-methyl-4-oxo-4H-pyran-3-olate) are reported herein. The complexes have been characterized by FTIR, CHN analysis, fluorescence spectroscopy, UV-visible spectroscopy, conductivity measurement and X-ray crystallography. The number of chelated maltolate ligands seems to influence their DNA recognition, topoisomerase I inhibition and antiproliferative properties.