A plasma cell variant of Castleman's disease treated successfully with cimetidine. Case report and review of the literature.

Castleman's disease is a rare benign condition of uncertain etiology, with several forms. It is postulated that a dysregulated inflammatory response may play a role in the pathogenesis of this disease. We report on a case of Castleman's disease treated with the histamine receptor-2 antagonist cimetidine with favourable response, suggesting that cimetidine may be helpful in the treatment of this disease.