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  • Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

Biochemical and biophysical research communications (2017-07-27)
Jihyun Lee, Goowon Yang, Young-Joo Kim, Quynh Hoa Tran, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
摘要

Persistent oxidative stress is recognized as a major cause of many pathological conditions as well as ageing. However, most clinical trials of dietary antioxidants have failed to produce successful outcomes in treating oxidative stress-induced diseases. Molecular hydrogen (H

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Sigma-Aldrich
Dorsomorphin, ≥98% (HPLC)
Sigma-Aldrich
DL-甘油醛-3-磷酸 溶液, 45-55 mg/mL in H2O
Sigma-Aldrich
四甲基罗丹明甲酯高氯酸盐, ≥95%