- Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice.
Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice.
Neuropharmacology (2017-07-22)
Gabriela C Segat, Mariane N Manjavachi, Daiane O Matias, Giselle F Passos, Cristina Setim Freitas, Robson Costa, João B Calixto
PMID28729222
摘要
Painful peripheral neuropathy is a common side effect of paclitaxel (PTX). The use of analgesics is an important component for management of PTX-induced peripheral neuropathy (PINP). However, currently employed analgesics have several side effects and are poorly effective. β-caryophyllene (BCP), a dietary selective CB