Lot-to-Lot Reproducibility of Monoclonal Antibody Analysis on Three Lots of Zenix® SEC-300 Columns
CONDITIONS
column
Zenix SEC-300, 30 cm x 7.8 mm I.D., 3 μm, 300 Å (Z777033)
mobile phase
150 mM Phosphate Buffer, pH 7
flow rate
1.0 mL/min
column temp.
Ambient
detector
UV, 214 nm
injection
10 μL
sample
2.5 mg/ml MAb
说明
分析说明
Exceptional lot-to-lot reproducibility is demonstrated for three lots of 3 micron Zenix SEC-300 columns for the release test of monoclonal antibody-based therapeutics. Monomer retention time, peak efficiency and peak height are shown to be virtually identical on the three lots.
法律信息
Zenix is a registered trademark of Sepax Technologies