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UHPLC Analysis of Flakka Compounds on Ascentis® Express HILIC

UHPLC Analysis of Flakka Compounds on Ascentis® Express HILIC application for HPLC

材料

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3,4-Methylenedioxypyrovalerone HCl (MDPV) solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

MDPBP hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Naphyrone hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

α-Pyrrolidinovalerophenone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

α-Pyrrolidinopropiophenone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Ascentis® Express HILIC, 2 μm UHPLC Column

2 μm particle size, L × I.D. 10 cm × 2.1 mm

CONDITIONS

column

Ascentis Express HILIC, 10 cm x 2.1 mm I.D., 2 μm (51409-U)

mobile phase

10 mM ammonium formate in acetonitrile:water (95:5)

flow rate

0.4 mL/min

column temp.

35 °C

detector

UV, 265 nm

injection

1 μL

sample

50 μg/mL in methanol:acetonitrile (10:90)

说明

分析说明

The rapid separation of the street drug Flakka (α-PVP) and related compounds is shown here on an Ascentis Express HILIC column. Highest grade UHPLC solvents were used to supply low background interference and low particulate contamination for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

法律信息

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany