211842
Brilliant Black BN
Dye content 60 %
别名:
Food Black 1
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关于此项目
经验公式（希尔记法）:
C28H17N5Na4O14S4
化学文摘社编号:
分子量:
867.68
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
28440
NACRES:
NA.47
EC Number:
219-746-5
MDL number:
form
powder
Quality Level
composition
Dye content, 60%
λmax
407 nm (2nd), 570 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Na+].[Na+].[Na+].[Na+].CC(=O)Nc1ccc(c2cc(c(\N=N\c3ccc(\N=N/c4ccc(cc4)S([O-])(=O)=O)c5ccc(cc35)S([O-])(=O)=O)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O
InChI
1S/C28H21N5O14S4.4Na/c1-14(34)29-23-10-11-24(50(42,43)44)20-13-25(51(45,46)47)27(28(35)26(20)23)33-32-22-9-8-21(18-7-6-17(12-19(18)22)49(39,40)41)31-30-15-2-4-16(5-3-15)48(36,37)38;;;;/h2-13,35H,1H3,(H,29,34)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47);;;;/q;4*+1/p-4/b31-30-,33-32+;;;;
InChI key
GMMAPXRGRVJYJY-OXYXOBGMSA-J
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Application
Brilliant Black BN has been used:
- in micronucleus and comet assays to evaluate its genotoxic effect.
- as a quenching agent in calcium mobilization assay.
- as a redox indicator in microbiological inhibition bioassay using Bacillus megaterium to detect tetracycline and macrolides in milk.
Biochem/physiol Actions
[4-acetamido-5-hydroxy-6-[7-sulfonato-4-(4-sulfonatophenylazo)-1-naphtylazo], also known as food black 1, belongs to the group of azo dyes. Brilliant Black BN is widely used as a food dye and pharmaceutical excipient. In addition, it also acts as an allosteric modulator of the adenosine A1 and A3 receptors and is generally used within calcium mobilization assays to reduce extracellular fluorescence.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Microbiological Method using Bacillus megaterium
with Fusidic Acid for Detection of Macrolides in Milk
with Fusidic Acid for Detection of Macrolides in Milk
Tumin M
Czech Journal of Food Sciences, 34, 9-15 (2016)
Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.
May LT
Molecular Pharmacology, 77, 678-686 (2010)
The evaluation of the genotoxicity of two commonly used food colors: Quinoline Yellow (E 104) and Brilliant Black BN (E 151).
Cellular & Molecular Biology Letters, 9, 107-122 (2004)
Calcium Mobilisation Assay in Response to Chemokine Stimulation
Cronshaw DG
Bio-protocol, 2 (2012)
Andrew Joiner et al.
Journal of dentistry, 36 Suppl 1, S8-14 (2008-07-23)
To investigate a new optical approach to tooth whitening by enhancing the measurement and perception of tooth whiteness using blue coloured materials deposited onto the tooth surface. Salivary pellicle coated human extracted teeth or polished enamel specimens were used as
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 211842-10G | 04061838771988 |
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