CN
BCAR3
breast cancer anti-estrogen resistance 3
别名:
NSP2, SH2D3B
物种:
Human BCAR3 (8412), Mouse Bcar3 (29815), Rat Bcar3 (310838), Zebrafish bcar3 (570610), chicken BCAR3 (424494), Domestic Rabbit BCAR3 (100352424), cow BCAR3 (506231), sheep BCAR3 (101106808), domestic cat BCAR3 (101099315), domestic guinea pig Bcar3 (100717989) ...展开
UniProtKB ID:
基因ID:
- Human(8412) Summary: Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(29815) breast cancer anti-estrogen resistance 3
- Rat(310838) breast cancer anti-estrogen resistance 3
- Zebrafish(570610) breast cancer anti-estrogen resistance 3
- chicken(424494) breast cancer anti-estrogen resistance 3
- Domestic Rabbit(100352424) breast cancer anti-estrogen resistance 3
- cow(506231) breast cancer anti-estrogen resistance 3
- sheep(101106808) breast cancer anti-estrogen resistance 3
- domestic cat(101099315) breast cancer anti-estrogen resistance 3
- domestic guinea pig(100717989) breast cancer anti-estrogen resistance 3
- Horse(100059015) breast cancer anti-estrogen resistance 3
- naked mole-rat(101704053) breast cancer anti-estrogen resistance 3
- dog(479941) breast cancer anti-estrogen resistance 3
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Antibodies
货号
说明
物种反应性
应用
Anti-BCAR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-BCAR3 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-BCAR3 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
western blot
Rabbit anti-BCAR3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
western blot