Skip to Content
Merck
CN

BCL2A1

BCL2-related protein A1

Synonyms:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
Species:
UniProtKB ID:
Gene ID:
  • Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(170929) BCL2-related protein A1
  • cow(282151) BCL2-related protein A1
  • chicken(395673) BCL2-related protein A1
  • dog(488770) BCL2-related protein A1
  • naked mole-rat(101702935) BCL2-related protein A1
  • domestic cat(768283) BCL2-related protein A1
  • sheep(101114560) BCL2-related protein A1
  • domestic cat(101086480) BCL2-related protein A1
  • domestic guinea pig(100732983) BCL2-related protein A1

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BCL2A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, pig
Application
ELISA
western blot
Anti-BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
camelidae, bat, bovine, chimpanzee, human
Application
immunohistochemistry
western blot
Anti BCL2 related protein A1 Antibody, clone 23GB4820, Rabbit Monoclonal, clone 23GB4820, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BCL2A1,
Species
human