Technical Article

Applied Filters:

facet content type:Technical Article

Showing 1-30 of 1977 results

Combining Permeability and Solubility Analyses in a Single Workflow

This article details the benefits of combining solubility and a non-cell based permeability assay (Parallel Artificial Membrane Permeation Assay; PAMPA) into a single workflow in which a portion of the filtrate from the MultiScreen® Solubility filter plate is added to

Phase I Drug Metabolism

Phase I biotransformation reactions introduce or expose functional groups on the drug with the goal of increasing the polarity of the compound. Although Phase I drug metabolism occurs in most tissues, the primary and first pass site of metabolism occurs

Directed Evolution

An overview of directed evolution and the methods for generating proteins with optimized or entirely new functions.

Myosin

Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere

Insulin-like Growth Factors (IGF)

GC Analysis of Spearmint Essential Oil on SLB®-IL59

-Cymene; Linalool; Menthol; α-Terpineol; Menthyl acetate

Mass Spectrometry

What is Mass Spectrometry or MS? What is it used for and how does it work? Read this detailed article with diagrams and example graphs to understand how to use mass spec in your research.

Determination of Stevioside and Rebaudioside A in Stevia leaves, beverages and food additives using HPTLC-MS

HPTLC-MS was used to analyze stevioside and rebaudioside in artificial sweeteners, stevia plants, cola and isotonic drinks with a minimum of sample preparation.

History of Thin-Layer Chromatography

Thin layer chromatography

GC Analysis of Permanent Gases and Light Hydrocarbons on Carboxen-1006 PLOT and a Packed Column (Carboxen® 1004)

Separation of Methane; Acetylene; Carbon monoxide; Water; Nitrogen; Carbon dioxide; Ethane; Ethylene

The Proper Storage and Handling of Volatile Analytical Standards

Properly storing and handling standards is critical to achieving accurate and reproducible analytical results.

FastWoRX for Faster and Greener Alternative to Liquid-Liquid Extraction

After filtration, the FastWoRX powder loaded with organic products can serve as a convenient input for flash chromatographic separation or other processing.

Principal Component Analysis (PCA) Evaluation of Seven Commercial Ionic Liquid Capillary GC Columns

In order to cover a broad range of possible solute-stationary phase interactions, 95 solutes with varied functional groups were selected to perform stationary phase characterization.

Synthesis and Biomedical Applications of Polyamino Acids

Aggregation-induced Emission Luminogens for Non-doped Organic Light-emitting Diodes

Organic Light-emitting Diodes (OLEDs) are solid-state devices that transform electrical energy into light. OLEDs are considered the next generation technology for high-resolution flexible displays and solid state lighting, attracting intense scientific and industrial interest.

Controlled Fabrication Methods for Tissue Engineering Constructs

Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.

Use of Iron Oxide Incorporated Conjugated Polymer Nanoparticles for Bioimaging

Our highly fluorescent iron oxide incorporated conjugated polymer nanoparticles (CPNs) have an iron oxide and semiconductor light emitting polymer core, encapsulated within a biocompatible surfactant. The multi-modal particles can be used in both fluorescence and magnetic resonance imaging. Learn more

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

Achieving High Efficiency in Organic Light-Emitting Devices

Electroluminescence of organic molecules has been a wellknown phenomenon for more than 50 years.

The Use of Block Copolymers in Nanoscale Patterning

This article reviews the use of block copolymers to coat a surface to make unique nanoscale patterns on a substrate (shown below). Using this method, as opposed to etching with a laser, can improve resolution from the current limit of

Organic Materials for Thin Film Transistors

AIE Luminogens: A Family of New Materials with Multifaceted Functionalities

AIE Luminogens - Family of new materials with multifaceted functionalities. Find some representative applications of the AIEgens

Efficient dye-sensitized solar cells for direct conversion of sunlight to electricity

Dye-sensitized solar cells directly convert sunlight to electricity

Polymer Analysis in Materials Science

Scientists at Sigma-Aldrich® routinely determine number-average molecular weight (Mn) by 1H NMR end-group analysis for polymers having Mn values under 3,000.

Materials Design Concepts for Efficient Blue OLEDs: A Joint Theoretical and Experimental Study

Water-Soluble Photoinitiators

The introduction of LAP and water-dispersible photoinitiator nanoparticles of TPO, enables the development of novel formulations for 3D bioprinting, tissue engineering applications, and device manufacturing.

Soluble Pentacene Precursors

Fabrication procedure of organic field effect transistor device using a soluble pentacene precursor.

Dendrons and Hyperbranched Polymers: Multifunctional Tools for Materials Chemistry

Dendrons in nanomaterials - Find features and benefits of polyester dendrons and hyperbranched polymer products.

Applications of Y-Shape Peg Derivatives for Drug Delivery

The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids are hydrolyzed by nucleases; and most small molecules are eliminated

Delivery of Nucleic Acids Using Polymers

Page 1 of 66