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Iupac Name
3-[(tert-butoxycarbonyl)amino]-2'-hydroxy-1,1'-biphenyl
Inchi Code
1S/C17H19NO3/c1-17(2,3)21-16(20)18-13-8-6-7-12(11-13)14-9-4-5-10-15(14)19/h4-11,19H,1-3H3,(H,18,20)
InChI key
HYJWABFIDNHSGT-UHFFFAOYSA-N
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此商品 | 615595 | 490865 | 490199 |
---|---|---|---|
assay 99% (CP) | assay - | assay 99% (CP) | assay - |
isotopic purity 99 atom % 13C | isotopic purity 98 atom % D | isotopic purity 99 atom % 13C | isotopic purity 99 atom % 13C |
mass shift M+2 | mass shift M+2 | mass shift M+2 | mass shift M+2 |
Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
form solid | form solid | form solid | form solid |
mp 137-140 °C (lit.) | mp 137-140 °C (lit.) | mp 52-54 °C (lit.) | mp 132-135 °C (dec.) (lit.) |
储存温度
Refrigerated
Purity
95%
Country of Origin
CN
Product Link
https://www.combi-blocks.com/cgi-bin/find.cgi?YA-1897
MSDS
https://www.combi-blocks.com/cgi-bin/find.cgi?YA-1897
法规信息
新产品
Kamonpan Sanachai et al.
RSC medicinal chemistry, 12(3), 430-438 (2021-05-29)
The Janus kinase (JAK) and epidermal growth factor receptor (EGFR) have been considered as potential targets for cancer therapy due to their role in regulating proliferation and survival of cancer cells. In the present study, the aromatic alkyl-amino analogs of
Kamonpan Sanachai et al.
ACS omega, 7(37), 33548-33559 (2022-09-27)
Janus kinases (JAKs) are nonreceptor protein tyrosine kinases that play a role in a broad range of cell signaling. JAK2 and JAK3 have been involved in the pathogenesis of common lymphoid-derived diseases and leukemia cancer. Thus, inhibition of both JAK2
Kamonpan Sanachai et al.
ACS omega, 7(37), 33587-33598 (2022-09-27)
Janus kinases (JAKs) are involved in a wide variety of cell signaling associated with T-cell and B-cell mediated diseases. The pathogenesis of common lymphoid-derived diseases and leukemia cancer has been implicated in JAK2 and JAK3. Therefore, to decrease the risk
Kamonpan Sanachai et al.
ACS omega, 5(1), 369-377 (2020-01-21)
Janus kinases (JAKs) are enzymes involved in signaling pathways that affect hematopoiesis and immune cell functions. JAK1, JAK2, and JAK3 play different roles in numerous diseases of the immune system and have also been considered as potential targets for cancer
Chalita Washington et al.
PLoS genetics, 16(6), e1008715-e1008715 (2020-06-20)
Dysregulation of the Ras oncogene in development causes developmental disorders, "Rasopathies," whereas mutational activation or amplification of Ras in differentiated tissues causes cancer. Rabex-5 (also called RabGEF1) inhibits Ras by promoting Ras mono- and di-ubiquitination. We report here that Rabex-5-mediated