Merck
CN

1.00590

SAFC

甘氨酸晶体

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

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别名:
甘氨酸, 氨基乙酸
线性分子式:
NH2CH2COOH
CAS号:
分子量:
75.07
Beilstein:
635782
MDL编号:
EC索引号:
200-272-2

Agency

BP
ChP
JP
Ph. Eur.
USP

质量水平

蒸汽压

0.0000171 Pa ( 25 °C)

描述

EMPROVE® EXPERT Ph Eur,BP,JP,USP

产品线

EMPROVE® EXPERT

检测方案

98.5-101.0% (calculated on dried substance, perchloric acid titration)

形式

crystalline
solid

technique(s)

inhibition assay: suitable

pH值(酸碱度)

5.9-6.4 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

soluble 250 g/L

密度

1.161 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

储存温度

2-30°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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一般描述

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Glycine is an amino acid which is used widely in the biopharma industry as stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine cryst. Emprove® Expert is especially suitable for high-risk applications.

生化/生理作用

脊髓中的抑制性神经递质,NMDA受体的变构调节器。

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

The substance 1.00590 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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