grade
pharmaceutical primary standard
API family
acetylcysteine
manufacturer/tradename
EDQM
mp
106-108 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
General description
本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。
如需进一步信息和支持，请访问现行药典网站。
如需进一步信息和支持，请访问现行药典网站。
Application
乙酰半胱氨酸EP参考标准品的预期用途是欧洲药典规定的实验室测试。
Biochem/physiol Actions
抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡，但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。
Packaging
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
Other Notes
可能适用相应的销售限制。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
M L A Sivilotti et al.
Clinical toxicology (Philadelphia, Pa.), 51(9), 855-863 (2013-10-19)
Haemodialysis is sometimes used for patients with massive acetaminophen overdose when signs of "mitochondrial paralysis" (lactic acidosis, altered mental status, hypothermia and hyperglycaemia) are present. The role of haemodialysis is debated, in part because the evidence base is weak and
Eduesley Santana-Santos et al.
The Annals of thoracic surgery, 97(5), 1617-1623 (2014-03-25)
The renoprotective effect of N-acetylcystein in patients undergoing coronary artery bypass graft surgery is controversial. We assessed the renoprotective effect of the highest dose of N-acetylcystein sanctioned for clinical use in a prospective, double-blind, placebo-controlled study including 70 chronic kidney
Michael Berk et al.
Trends in pharmacological sciences, 34(3), 167-177 (2013-02-02)
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant glutathione, neurotrophins, apoptosis, mitochondrial function, and inflammatory pathways. This review summarises the areas where the mechanisms of action of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A0150000 | 04061833799185 |