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F0290000

Flutrimazole

Name: Flutrimazole
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole

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关于此项目

经验公式（希尔记法）:

C₂₂H₁₆F₂N₂

化学文摘社编号:

119006-77-8

分子量:

346.37

MDL number:

MFCD00865591

UNSPSC Code:

41116107

NACRES:

NA.24

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属性

grade

pharmaceutical primary standard

API family

flutrimazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Fc1c(cccc1)C([n]4cncc4)(c3ccc(cc3)F)c2ccccc2

InChI

1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H

InChI key

QHMWCHQXCUNUAK-UHFFFAOYSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Flutrimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A double-blind, randomized comparative trial: flutrimazole 1% solution versus bifonazole 1% solution once daily in dermatomycoses.

del Palacio et al.

Mycoses, 38(9-10), 395-403 (1995-09-01)

In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% solution were compared with bifonazole 1% solution, applied once daily for 4 weeks, in 40 patients with culturally proven dermatophytosis or cutaneous candidosis. Forty patients with mycologically proven

Flutrimazole 1% dermal cream in the treatment of dermatomycoses: a multicentre, double-blind, randomized, comparative clinical trial with bifonazole 1% cream. Efficacy of flutrimazole 1% dermal cream in dermatomycoses. Catalan Flutrimazole Study Group.

A Alomar et al.

Dermatology (Basel, Switzerland), 190(4), 295-300 (1995-01-01)

Flutrimazole is a new imidazole derivate. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. To compare the efficacy and tolerability of flutrimazole cream 1%

In vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity.

J García Rafanell et al.

Arzneimittel-Forschung, 42(6), 836-840 (1992-06-01)

1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (MIC = 0.025-5.0 micrograms/ml). In most of these

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货号	GTIN
F0290000	04061833611081