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H0800000

Homatropine hydrobromide

Name: Homatropine hydrobromide
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

DL-Homatropine hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide, Tropine mandelate hydrobromide

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关于此项目

经验公式（希尔记法）:

C₁₆H₂₁NO₃ · HBr

化学文摘社编号:

51-56-9

分子量:

356.25

NACRES:

NA.24

PubChem Substance ID:

329815135

UNSPSC Code:

41116107

MDL number:

MFCD00012676

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属性

grade

pharmaceutical primary standard

API family

homatropine

manufacturer/tradename

EDQM

mp

214-217 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

InChI key

DWSGTFTVBLXELC-UHFFFAOYSA-N

说明

General description

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Intramuscular ophthalmic homatropine vs. atropine to prevent lethality in rates with dichlorvos poisoning.

Sean M Bryant et al.

Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2(4), 156-159 (2007-12-12)

Most hospitals lack a sufficient supply of atropine to treat, simultaneously, patients poisoned with multiple organophosphorous compound (OC) or nerve agent. The presence of a ubiquitous alternate antidote would prove useful if mass poisoning occurred. Our objective was to evaluate

Topical chloramphenicol prophylaxis is of dubious benefit in corneal abrasion.

Joseph Ting

Emergency medicine Australasia : EMA, 23(2), 231-231 (2011-04-15)

Bilateral microbial keratitis in highly active antiretroviral therapy-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a case series.

Ritika Sachdev et al.

Ocular immunology and inflammation, 19(5), 343-345 (2011-08-13)

To report three cases of bilateral microbial keratitis in eyes with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) induced by highly active antiretroviral therapy (HAART) in patients of acquired immune deficiency syndrome (AIDS). A case series. A detailed clinical

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货号	GTIN
H0800000	04061833811412