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Merck
CN

O1008

油酸

≥99% (GC)

别名:

9Z-十八碳烯酸,顺式-烯烃油酸, 顺式-9-十八碳烯酸, 反油酸

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关于此项目

线性分子式:
CH3(CH2)7CH=CH(CH2)7COOH
化学文摘社编号:
分子量:
282.46
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
204-007-1
Beilstein/REAXYS Number:
1726542
MDL number:
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biological source

plant (Sunflower)

Quality Level

vapor pressure

1 mmHg ( 176 °C)

assay

≥99% (GC)

form

viscous liquid

color

colorless to very faintly yellow

refractive index

n20/D 1.459 (lit.)

bp

194-195 °C/1.2 mmHg (lit.)

mp

13-14 °C (lit.)

solubility

H2O: insoluble (practically), alcohol: soluble, benzene: soluble, chloroform: soluble, oil: soluble (fixed and volatile)

density

0.89 g/mL at 25 °C (lit.)

application(s)

life science and biopharma
lipidomics

functional group

oleic acid

lipid type

unsaturated FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI key

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

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General description

油酸 (OA) 是一种非必需脂肪酸,属于单不饱和脂肪酸 (MUFA),橄榄油中富含这一成分。已有报道称,这种成分可从甘油三酯和偏甘油酯混合物中的定量去除。OA广泛用作稳定磁性纳米颗粒的表面活性剂。目前已制备出OA包覆的单分散磁铁矿纳米颗粒(7和19nm)。

Application

油酸可用于:
  • 研究脂肪酸对胃癌 (GC) 的影响
  • 诱导细胞培养物中的脂滴形成
  • 作为磁流变液制剂中的添加剂。
油酸可用于制备10-羟基十八烷酸和10-羟基十八烷酸甲酯。

Biochem/physiol Actions

众所周知,油酸可以改善免疫功能和健康。膳食补充这种脂肪酸有助于降低胆固醇水平、动脉粥样硬化风险、血压及宿主对移植物的反应。油酸经证有抗炎作用,有助对抗自身免疫性疾病。它还可以改善乳腺癌状况。油酸可引起多种生理效应,如肝细胞中的蛋白激酶C活化、氧化磷酸化解偶联及2,4-二硝基苯酚−刺激的 ATP 酶抑制。通过添加血清白蛋白可以逆转这种作用。

Other Notes

如需了解生化试剂系列的更多信息,请填写此表

存储类别

10 - Combustible liquids

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup


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THE STEREOSPECIFIC CONVERSION OF STEARIC ACID TO OLEIC ACID.
G J SCHROEPFER et al.
The Journal of biological chemistry, 240, 54-63 (1965-01-01)
Oleic acid coating on the monodisperse magnetite nanoparticles.
Zhang L, et al.
Applied Surface Science, 253(5), 2611-2617 (2006)
Influence of graphite flakes on the strength of magnetorheological fluids at high temperature and its rheology
Thakur MK and Sarkar C
IEEE Transactions on Magnetics, 56(5) (2020)
CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3?/?-catenin pathway
Pan J, et al.
Journal of Experimental & Clinical Cancer Research, 38 (2019)
Kun Huang et al.
Journal of hepatology, 66(5), 962-977 (2016-12-17)
PARP1 is a key mediator of cellular stress responses and critical in multiple physiological and pathophysiological processes of cells. However, whether it is involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) remains elusive. We analysed PARP1 activity in

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实验方案

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全球贸易项目编号

货号GTIN
O1008-1G04061835547135
O1008-5G04061835547142
O1008-25G04061835507085

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