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关于此项目
经验公式(希尔记法):
C9H15N5O
化学文摘社编号:
分子量:
209.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
minoxidil
manufacturer/tradename
EDQM
mp
272-274 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
General description
本品按现行药典规定交付。该产品的所有支持信息,包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持,请见现行药典的网站。
Application
用于系统适用性的米诺地尔EP参考标准品的预期用途是欧洲药典规定的实验室测试。
Biochem/physiol Actions
激活 ATP 激活的 K+ 通道;血管扩张剂;减缓或停止脱发,促进头发再生。
Packaging
本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录。
Other Notes
可能适用相应的销售限制条件。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
R L DeVillez
Dermatologic clinics, 8(2), 367-375 (1990-04-01)
Topical minoxidil is a trichogenic agent that stimulates the hair follicle via the vasoactive metabolite minoxidil sulfate without any evidence of antiandrogen activity or an effect on the immune system. Less than 5% of the applied dose is absorbed. The
Susumu Otomo
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 119(3), 167-174 (2002-03-28)
The length and size of hair are depend on the anagen term in its hair cycle. It has been reported that the some cell growth factors, such as VEGF, FGF-5S, IGF-1 and KGF, induce the proliferation of cells in the
Minoxidil use in female alopecia.
W M Wong et al.
The Annals of pharmacotherapy, 28(7-8), 890-891 (1994-07-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Y0001432 | 04061833807781 |
