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经验公式(希尔记法):
C9H15N5O
化学文摘社编号:
分子量:
209.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
米诺地尔,系统适用性测试标准品, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
minoxidil
manufacturer/tradename
EDQM
mp
272-274 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
用于系统适用性的米诺地尔EP参考标准品的预期用途是欧洲药典规定的实验室测试。
Biochem/physiol Actions
激活 ATP 激活的 K+ 通道;血管扩张剂;减缓或停止脱发,促进头发再生。
General description
本品按现行药典规定交付。该产品的所有支持信息,包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持,请见现行药典的网站。
Other Notes
可能适用相应的销售限制条件。
Packaging
本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
S E Whitmore
Archives of dermatology, 128(5), 653-656 (1992-05-01)
The correct selection of vehicles for patch testing specific substances is essential in the evaluation of suspected allergic contact dermatitis. A reaction to a chemical may be dependent not only on the concentration tested but also on the vehicle in
D A Sica et al.
Journal of clinical hypertension (Greenwich, Conn.), 3(2), 110-114 (2001-06-21)
Minoxidil is a direct vasodilator that has been in use for over two decades. It is used primarily to reduce blood pressure in hypertensives who have been poorly controlled on various multidrug regimens. Although minoxidil is extremely effective, its usefulness
Minoxidil use in female alopecia.
W M Wong et al.
The Annals of pharmacotherapy, 28(7-8), 890-891 (1994-07-01)
Domenic A Sica
Journal of clinical hypertension (Greenwich, Conn.), 6(5), 283-287 (2004-05-11)
Minoxidil is a direct vasodilator introduced in the early 1970s for the treatment of hypertension. It is capable of reducing blood pressure in most persons with resistant hypertension where therapy has failed with multidrug regimens. Minoxidil's effect can be limited
Alfredo Rossi et al.
Recent patents on inflammation & allergy drug discovery, 6(2), 130-136 (2012-03-14)
Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, was first introduced, exclusively as an oral drug, to treat high blood pressure. It was however discovered to have the important side-effect
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