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关于此项目
经验公式(希尔记法):
C9H15N5O
化学文摘社编号:
分子量:
209.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
minoxidil
manufacturer/tradename
EDQM
mp
272-274 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
本品按现行药典规定交付。该产品的所有支持信息,包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持,请见现行药典的网站。
Application
用于系统适用性的米诺地尔EP参考标准品的预期用途是欧洲药典规定的实验室测试。
Biochem/physiol Actions
激活 ATP 激活的 K+ 通道;血管扩张剂;减缓或停止脱发,促进头发再生。
Packaging
本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录。
Other Notes
可能适用相应的销售限制条件。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Marc R Avram et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 28(10), 894-900 (2002-11-02)
Over the last decade surgical management of hair loss has become an increasingly popular and satisfying procedure for both men and women, as innovations in donor harvesting, graft size, and hairline design have resulted in consistently natural-appearing hair restoration. In
Topical minoxidil for hair loss in women.
D Hong et al.
DICP : the annals of pharmacotherapy, 24(11), 1062-1063 (1990-11-01)
[The therapy of androgenetic alopecia with minoxidil].
A Bammel et al.
Deutsche medizinische Wochenschrift (1946), 118(21), 787-789 (1993-05-28)
R C Savin et al.
Dermatologic clinics, 11(1), 55-64 (1993-01-01)
The study and common use of minoxidil have legitimized research in common baldness. Prior to this time, with rare exception, the field was dominated by charlatans and "snake oil merchants." Minoxidil has opened the door to scientific inquiry and allowed
T P Dooley
Experimental dermatology, 8(4), 328-329 (1999-08-10)
Cytosolic sulfotransferases (ST) catalyze the sulfation of various phenolic agents, catecholamines, thyroid hormones, steroids, drugs, and procarcinogens, usually resulting in the inactivation and subsequent excretion of the compound. My laboratory's efforts have focused on the cloning of the human phenol-sulfating
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