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经验公式（希尔记法）:
C8H15N7O2S3
化学文摘社编号:
分子量:
337.45
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
法莫替丁, British Pharmacopoeia (BP) Reference Standard
InChI
1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
SMILES string
N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
InChI key
XUFQPHANEAPEMJ-UHFFFAOYSA-N
grade
pharmaceutical primary standard
agency
BP
API family
famotidine
form
solid
shelf life
limited shelf life, expiry date on the label
packaging
pkg of 100 mg
manufacturer/tradename
BP
storage condition
OK to freeze
color
white
mp
162-165 °C
solubility
water: insoluble
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
shipped in
ambient
storage temp.
2-8°C
Gene Information
human ... HRH2(3274)
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Biochem/physiol Actions
H2组胺受体拮抗剂；抗溃疡剂。
Application
Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Famotidine Tablets
Also used in monographs such as:
General description
Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).
Packaging
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Famotidine
British Pharmacopeia
British Pharmacopoeia, 29(1-2), 247-254 (2020)
Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
Campbell AN and Sherma J
Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)
Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
Kelani KM, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
Development and validation of chromatographic methods for simultaneous determination of ibuprofen and famotidine in presence of related substances in pharmaceutical formulations
Elzanfaly ES, et al.
Acta Chimica Slovenica, 62(1) (2014)
Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
Helali N and Monser L
Journal of Separation Science, 31(2) (2008)
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