产品名称
羧甲司坦, European Pharmacopoeia (EP) Reference Standard
SMILES string
N[C@@H](CSCC(O)=O)C(O)=O
InChI key
GBFLZEXEOZUWRN-VKHMYHEASA-N
InChI
1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
grade
pharmaceutical primary standard
API family
carbocisteine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
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Application
Carbocisteine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Masayuki Hanaoka et al.
Chest, 139(5), 1101-1108 (2010-09-18)
Chronic inflammation, imbalance of proteolytic and antiproteolytic activities, oxidative stress, and apoptosis of lung structural cells contribute to the pathogenesis of COPD. There is increasing evidence that carboxymethylcysteine (also known as carbocisteine) (CMC), which is commonly used for its mucoactive
Boontarika Boonyapiwat et al.
The Journal of pharmacy and pharmacology, 63(4), 558-564 (2011-03-16)
The aim of this investigation was to provide in-vitro enzyme kinetic data to support the hypothesis that the in-vivo heterozygous dominant phenotype for phenylalanine monooxygenase (hPAH) was responsible for the S-oxidation polymorphism in the metabolism of S-carboxymethyl-l-cysteine reported in humans.
Matthew Thomas Hardison et al.
Frontiers in bioscience (Elite edition), 4, 2402-2409 (2012-06-02)
Several chronic lung diseases have been linked to cigarette smoking (Chronic Obstructive Pulmonary Disease (COPD), and cancer are associated with increased tobacco use). We recently described a collagen fragment, proline-glycine-proline (PGP), chemotactic for neutrophils, that appears to play a role
Qing Zhai et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 67(3-4), 215-221 (2012-05-26)
Hepatic injury induced by oxaliplatin has been reported. Even though agents are available that reduce oxaliplatin-induced hepatocyte toxicity, their mode of action has remained obscure. In the present study, hepatic L02 cells were incubated with different combinations of oxaliplatin and
Kenichiro Kudo et al.
Internal medicine (Tokyo, Japan), 52(1), 97-100 (2013-01-08)
A 32-year-old male with CATCH22 syndrome presented with a high fever and productive cough after taking drugs for acute bronchitis, including (L)-carbocisteine. Chest radiography revealed ground-glass opacities in the bilateral lung fields. He had a history of similar pneumonia. Under
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