产品名称
对羟基苯甲酸甲酯, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
SMILES string
COC(=O)c1ccc(O)cc1
InChI key
LXCFILQKKLGQFO-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
parabens
manufacturer/tradename
EDQM
mp
125-128 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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General description
Other Notes
可能适用相应的销售限制。
Packaging
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
Application
本欧洲药典参考标准仅适用于欧洲药典中明确规定的用途。不保证其适用于任何其他用途，并由用户自行负责。本标准不适用于人类或动物。
根据《欧洲药典》，用于制备以下给定溶液：
根据《欧洲药典》，用于制备以下给定溶液：
- 参考溶液（a）和（b），根据专著 0409 和 1262，用于对羟基苯甲酸甲酯和对羟基苯酸甲酯钠的鉴定、相关物质测试和测定
- 参考溶液（c），根据 1999 年专论，使用液相色谱法检测尼呋噻嗪中相关物质（2.2.29）
- 参考溶液（b），根据专著2134，使用薄层色谱法鉴定对羟基苯甲酸乙酯钠（一般文本2.2.27）
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
334.4 °F
flash_point_c
168 °C
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Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses
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