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经验公式(希尔记法):
C9H15N5O
化学文摘社编号:
分子量:
209.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
米诺地尔, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
minoxidil
manufacturer/tradename
EDQM
mp
272-274 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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Biochem/physiol Actions
激活 ATP 激活的 K+ 通道;血管扩张剂;减缓或停止脱发,促进头发再生。
Application
Minoxidil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
Chester L Bowen et al.
Bioanalysis, 4(23), 2823-2832 (2012-12-12)
Stabilization of phase II metabolites is an important consideration during bioanalytical method development, method validation and sample analysis. Generic approaches to stabilize these metabolites during storage in liquid-based matrices include pH adjustment of samples prior to storage and/or temperature control;
Esther J van Zuuren et al.
The Cochrane database of systematic reviews, 5(5), CD007628-CD007628 (2012-05-18)
Female pattern hair loss, or androgenic alopecia, is the most common type of hair loss affecting women. It is characterised by progressive shortening of the duration of the growth phase of the hair with successive hair cycles, and progressive follicular
E J van Zuuren et al.
The British journal of dermatology, 167(5), 995-1010 (2012-10-09)
Female pattern hair loss (FPHL) or androgenic alopecia is the most common type of hair loss affecting women with reduced hair density and can have a serious psychological impact. It is characterized by progressive replacement of slow cycling terminal hair
S E Whitmore
Archives of dermatology, 128(5), 653-656 (1992-05-01)
The correct selection of vehicles for patch testing specific substances is essential in the evaluation of suspected allergic contact dermatitis. A reaction to a chemical may be dependent not only on the concentration tested but also on the vehicle in
Guilherme Martins Gelfuso et al.
Journal of pharmaceutical sciences, 102(5), 1488-1494 (2013-03-02)
Although minoxidil (MX) is a drug known to stimulate hair growth, the treatment of androgenic alopecia could be improved by delivery strategies that would favor drug accumulation into the hair follicles. This work investigated in vitro the potential of iontophoresis
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