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经验公式（希尔记法）:
C9H15N5O
化学文摘社编号:
分子量:
209.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
米诺地尔, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
minoxidil
manufacturer/tradename
EDQM
mp
272-274 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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Biochem/physiol Actions
激活 ATP 激活的 K+ 通道；血管扩张剂；减缓或停止脱发，促进头发再生。
Application
Minoxidil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
E J van Zuuren et al.
The British journal of dermatology, 167(5), 995-1010 (2012-10-09)
Female pattern hair loss (FPHL) or androgenic alopecia is the most common type of hair loss affecting women with reduced hair density and can have a serious psychological impact. It is characterized by progressive replacement of slow cycling terminal hair
R Colamarino et al.
Annales de medecine interne, 141(5), 425-428 (1990-01-01)
Topical minoxidil, used in the treatment of baldness, has been commercially available since 1987. Its systemic side effects are rare. We observed an as yet unreported "polymyalgia syndrome" in four otherwise healthy males whose sole medication was topically applied minoxidil.
A G Messenger et al.
The British journal of dermatology, 150(2), 186-194 (2004-03-05)
We have known for over 30 years that minoxidil stimulates hair growth, yet our understanding of its mechanism of action on the hair follicle is very limited. In animal studies, topical minoxidil shortens telogen, causing premature entry of resting hair
R L DeVillez
Dermatologic clinics, 8(2), 367-375 (1990-04-01)
Topical minoxidil is a trichogenic agent that stimulates the hair follicle via the vasoactive metabolite minoxidil sulfate without any evidence of antiandrogen activity or an effect on the immune system. Less than 5% of the applied dose is absorbed. The
R C Savin et al.
Dermatologic clinics, 11(1), 55-64 (1993-01-01)
The study and common use of minoxidil have legitimized research in common baldness. Prior to this time, with rare exception, the field was dominated by charlatans and "snake oil merchants." Minoxidil has opened the door to scientific inquiry and allowed
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