SMILES string
[Na+].[Na+].N(\N=C2/C=C(C(=O)C=C/2)C(=O)[O-])c1cc(c(cc1)O)C(=O)[O-]
InChI
1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,15,17H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-8-;;
InChI key
QQWFSVYVHLECFP-XBPUGJBTSA-L
grade
pharmaceutical primary standard
API family
olsalazine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Olsalazine sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
[Oral therapy instead of enemas].
MMW Fortschritte der Medizin, 145(8), 56-56 (2003-03-29)
Gerassimos J Mantzaris et al.
The American journal of gastroenterology, 99(6), 1122-1128 (2004-06-08)
The aim of this prospective study was to assess whether the coadministration of azathioprine (AZA) and olsalazine is superior to AZA monotherapy in maintaining remission of steroid-dependent ulcerative colitis (UC). Patients with steroid-dependent UC in remission were randomized to receive
Laurie M Edmond et al.
Inflammatory bowel diseases, 9(1), 10-17 (2003-03-27)
The toxic, bacterial metabolite sulfide is implicated in ulcerative colitis. Ulcerative colitis patients taking 5-aminosalicylic acid-containing drugs have lower fecal sulfide levels than those not taking these drugs. The effects of sulfasalazine, balsalazide, olsalazine, and 5-aminosalicylic acid on sulfide production
B Nigović et al.
Die Pharmazie, 57(7), 468-470 (2002-08-10)
The electrochemical behavior of 2-hydroxy-5-[(4-sulfophenyl)azo]benzoic acid, 2-hydroxy-5-[(3-sulfophenyl)azo]benzoic acid and 2-hydroxy-5-[(2-sulfophenyl)-azo]benzoic acid was investigated by cyclic voltammetry using a glassy carbon electrode. The influence of the pH and position of the substituents on the reaction pathway has been studied. The results
Yue-Meng Wan et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 22(5), 486-493 (2012-01-12)
We aimed to investigate the therapeutic effects of Peifeikang, a probiotics compound, on colitis in rats induced by trinitrobenzene sulfonic acid and to elucidate its potential mechanism. We evaluated the therapeutic effects of Peifeikang by analysis of the disease activity
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