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Merck
CN

P1700000

毛果芸香碱 硝酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

Pilocarpine nitrate salt

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关于此项目

经验公式(希尔记法):
C11H16N2O2 · HNO3
化学文摘社编号:
分子量:
271.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4171406
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InChI

1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1

SMILES string

O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C

InChI key

PRZXEPJJHQYOGF-GNAZCLTHSA-N

grade

pharmaceutical primary standard

API family

pilocarpine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pilocarpine nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

非选择性毒蕈碱型乙酰胆碱受体激动剂。
非选择性毒蕈碱型乙酰胆碱受体激动剂;用于建立癫痫的实验模型。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Flame over circleSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2

存储类别

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marcele Jardim Pimentel et al.
Anticancer research, 34(4), 1993-1999 (2014-04-03)
There is controversy concerning the effect of pilocarpine in the reversal of radio-induced xerostomia; however, the tests are usually performed at the end of radiotherapy. The present study evaluated the radioprotective effects of pilocarpine when ingested during radiation treatment. Eleven
Barina Aqil et al.
Archives of pathology & laboratory medicine, 138(7), 920-922 (2014-02-27)
All positive screening of newborns for cystic fibrosis using the dried blood spot 2-tiered immunoreactive trypsinogen/DNA method requires subsequent sweat chloride testing for confirmation. Obtaining an adequate volume of sweat to measure chloride is a challenge for many cystic fibrosis
G Asuntha et al.
Indian journal of experimental biology, 53(1), 31-35 (2015-02-14)
Argemone mexicana (L.) has a role in the treatment of epileptic disorders in Indian traditional system of medicine. We studied its effect on induced status epilepticus (SE) and oxidative stress in rats. SE was induced in male albino rats by
Yuan-yuan Zhang et al.
Acta pharmacologica Sinica, 35(9), 1137-1149 (2014-08-05)
The non-neuronal acetylcholine system (NNAS) in endothelial cells participates in modulating endothelial function, vascular tone, angiogenesis and inflammation, thus plays a critical role in cardiovascular diseases. In this study, we used a proteomic approach to study potential downstream receptor-effectors of
Lin He et al.
Experimental eye research, 125, 244-255 (2014-07-02)
This study was undertaken to understand the role of anterior chamber pressure (ACP) during pharmacological and Edinger-Westphal (EW) stimulated accommodation in anesthetized monkeys. Experiments were performed on one iridectomized eye each of 7 anesthetized adolescent rhesus monkeys. Accommodation was induced

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