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Merck
CN

P3750000

异丙安替比林

European Pharmacopoeia (EP) Reference Standard

别名:

4-Isopropylantipyrine, 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one, 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, Isopropylphenazone, Propyphenazone

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关于此项目

经验公式(希尔记法):
C14H18N2O
化学文摘社编号:
分子量:
230.31
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
204533
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grade

pharmaceutical primary standard

API family

propyphenazone 

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2

InChI

1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3

InChI key

PXWLVJLKJGVOKE-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propyphenazone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sebastian Zühlke et al.
Journal of chromatography. A, 1050(2), 201-209 (2004-10-29)
A new analytical method applying in situ derivatization was developed to enable the extraction of polar drug metabolites from water samples by solid-phase extraction (SPE). An additional derivatization by silylation was used to enhance the sensitivity of analyte detection by
Rosario Rodil et al.
Water research, 46(7), 2457-2468 (2012-03-03)
Chlorination is one of the most popular disinfection steps for water treatment in Europe. However, chlorine can react with pharmaceuticals and other micropollutants leading to either their elimination or by-products being formed. These by-products are frequently not identified and therefore
Deniz Emre et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 847(2), 126-132 (2006-10-19)
A new micellar electrokinetic capillary chromatographic method has been developed to analyze the pharmaceutical preparations containing ternary combination of paracetamol (PAR), caffeine (CAF) and propyphenazone (PRO). Best results were obtained by using 20mM pH 9.0 borate buffer containing 30mM sodiumdodecylsulphate
Acute inferior myocardial infarction with low atrial rhythm due to propyphenazone: Kounis syndrome.
Ahmet Akyel et al.
International journal of cardiology, 148(3), 352-353 (2010-06-15)
David Costa et al.
Free radical biology & medicine, 40(4), 632-640 (2006-02-07)
The risk of agranulocytosis associated with the use of pyrazolone drugs at therapeutical doses and for short periods of time has been considered to be very low. However, little or no attention at all has been devoted to the possible

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货号GTIN
P375000004061833814512

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