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Merck
CN

PHR1120

棕榈酸

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

C16:0, NSC 5030, 十六酸, 棕榈酸

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关于此项目

线性分子式:
CH3(CH2)14COOH
化学文摘社编号:
57-10-3
分子量:
256.42
Beilstein:
607489
EC 号:
200-312-9
MDL编号:
MFCD00002747
UNSPSC代码:
41116107
PubChem化学物质编号:
329823141
NACRES:
NA.24

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. P0090000
traceable to USP 1492007

蒸汽压

10 mmHg ( 210 °C)

API类

palmitic acid

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

沸点

271.5 °C/100 mmHg (lit.)

mp

61-62.5 °C (lit.)

密度

0.852 g/mL at 25 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CCCCCCCCCCCCCCCC(O)=O

InChI

1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

InChI key

IPCSVZSSVZVIGE-UHFFFAOYSA-N

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相关类别

一般描述

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。棕榈酸是人乳脂肪酸的主要成分。在针叶樱桃、海杂草及山茱萸的风干果实中亦有发现。

应用

这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

其他说明

想要查看本品的检验报告示例，请在下框中输入LRAA6510。这只是一个示例证书，可能与您收到的批次不符。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。

储存分类代码

11 - Combustible Solids

WGK

nwg

闪点(°F)

235.4 °F

闪点(°C)

113 °C

分析证书(COA)

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B Vessby et al.
Diabetologia, 37(10), 1044-1050 (1994-10-01)
Recent data indicate that peripheral insulin sensitivity may be influenced by dietary fat quality and skeletal muscle phospholipid fatty acid composition. During a health survey of 70-year-old men insulin sensitivity was measured by the euglycaemic hyperinsulinaemic clamp technique and the
Jonas Sieber et al.
The American journal of pathology, 183(3), 735-744 (2013-07-23)
Type 2 diabetes mellitus is characterized by dyslipidemia with elevated free fatty acids (FFAs). Loss of podocytes is a hallmark of diabetic nephropathy, and podocytes are highly susceptible to saturated FFAs but not to protective, monounsaturated FFAs. We report that
Hjalti Kristinsson et al.
Endocrinology, 154(11), 4078-4088 (2013-09-17)
Free fatty acids (FFAs) have pleiotropic effects on the pancreatic β-cell. Although acute exposure to FFAs stimulates glucose-stimulated insulin secretion (GSIS), prolonged exposure impairs GSIS and causes apoptosis. FFAs exert their effects both via intracellular metabolism and interaction with the
Mathieu Blanc et al.
Biochemical Society transactions, 41(1), 84-88 (2013-01-30)
S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modification plays a critical role for pathogens of all
Sanja Blaskovic et al.
The FEBS journal, 280(12), 2766-2774 (2013-04-05)
S-palmitoylation is post-translational modification, which consists in the addition of a C16 acyl chain to cytosolic cysteines and which is unique amongst lipid modifications in that it is reversible. It can thus, like phosphorylation or ubiquitination, act as a switch.
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