PHR1538
(+)-伪麻黄碱 盐酸盐
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
(+)-ψ-麻黄碱 盐酸盐, (1S,2S)-2-甲氨基-1-苯丙醇 盐酸盐, d-伪麻黄碱 盐酸盐, d-异麻黄碱 盐酸盐
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线性分子式:
C6H5CH[CH(NHCH3)CH3]OH·HCl
化学文摘社编号:
分子量:
201.69
UNSPSC Code:
12352210
NACRES:
NA.24
PubChem Substance ID:
EC Number:
206-462-1
Beilstein/REAXYS Number:
3915112
MDL number:
InChI
1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10+;/m0./s1
SMILES string
Cl.CN[C@@H](C)[C@@H](O)c1ccccc1
InChI key
BALXUFOVQVENIU-KXNXZCPBSA-N
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. P3850000, traceable to USP 1581005
API family
pseudoephedrine
CofA
current certificate can be downloaded
packaging
pkg of 250 mg
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
185-188 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Application
Pseudoephedrine hydrochloride may be used as a reference standard for the determination of the analyte in pharmaceutical formulations by high-performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
非选择性肾上腺素激动剂;减充血剂
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2625 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
T G Altuntas et al.
Journal of pharmaceutical and biomedical analysis, 17(1), 103-109 (1998-06-03)
In this study, fourth derivative spectrophotometry and high performance liquid chromatography (HPLC) have been used and described for the quantitative determination of acrivastine (I) and pseudoephedrine hydrochloride (II) in their pharmaceutical capsules form (Duact). In the former method, d4A/d gamma
Full and fractionated experimental designs for robustness testing in the high-performance liquid chromatographic analysis of codeine phosphate, pseudoephedrine hydrochloride and chlorpheniramine maleate in a pharmaceutical preparation.
Ragonese R, et al.
Journal of Chromatography A, 870(1-2), 45-51 (2000)
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