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Merck
CN

PHR3002

硫酸阿扎那韦 硫酸酯

pharmaceutical secondary standard, certified reference material

别名:

Atazanavir sulfate, (3S,8S,9S,12S)-1,14-Dimethyl-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate sulfate

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关于此项目

经验公式（希尔记法）:
C38H52N6O7 · H2SO4
化学文摘社编号:
229975-97-7
分子量:
802.93
NACRES:
NA.24
UNSPSC Code:
41116107

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产品名称

硫酸阿扎那韦 硫酸酯, pharmaceutical secondary standard, certified reference material

InChI

1S/C38H52N6O7.H2O4S/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28;1-5(2,3)4/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47);(H2,1,2,3,4)/t29-,30-,31+,32+;/m0./s1

InChI key

DQSGVVGOPRWTKI-QVFAWCHISA-N

SMILES string

O[C@@H](CN(CC1=CC=C(C2=CC=CC=N2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)[C@@H](NC([C@@H](NC(OC)=O)C(C)(C)C)=O)CC3=CC=CC=C3.O=S(O)OO

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0002059
traceable to USP 1044334

API family

atazanavir

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

pharmaceutical

storage temp.

2-8°C

Quality Level

300

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相关类别

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Antiviral HIV Protease Inhibitor
Atazanavir sulfate is the prodrug of Atazanavir, an antiviral HIV protease inhibitor.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

hcodes

H318,H372

Hazard Classifications

Eye Dam. 1 - STOT RE 1

target_organs

Heart,Liver

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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