S2100000
磺胺甲噁唑
European Pharmacopoeia (EP) Reference Standard
别名:
4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N 1 -（5-甲基异恶唑-3-基）磺胺
等级
pharmaceutical primary standard
API类
sulfamethoxazole
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI
1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI key
JLKIGFTWXXRPMT-UHFFFAOYSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Sulfamethoxazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 2 - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
Trimethoprim-sulfamethoxazole-associated aseptic meningitis: case reports and review of the literature.
A M Joffe et al.
The American journal of medicine, 87(3), 332-338 (1989-09-01)
Alejandro Hoberman et al.
The New England journal of medicine, 370(25), 2367-2376 (2014-05-06)
Children with febrile urinary tract infection commonly have vesicoureteral reflux. Because trial results have been limited and inconsistent, the use of antimicrobial prophylaxis to prevent recurrences in children with reflux remains controversial. In this 2-year, multisite, randomized, placebo-controlled trial involving
P G Spitzer et al.
Reviews of infectious diseases, 8(3), 427-430 (1986-05-01)
A 55-year-old female recipient of an orthotopic liver transplant, who was receiving azathioprine, prednisone and cyclosporin, developed bacteremia due to Listeria monocytogenes. Because of a penicillin allergy, the patient was treated primarIly with trimethoprim-sulfamethoxazole, to which she responded well. The
Trimethoprim-sulfamethoxazole: an assessment of more than 12 years of use.
A J Salter
Reviews of infectious diseases, 4(2), 196-236 (1982-03-01)
Raquel González et al.
PLoS medicine, 11(9), e1001735-e1001735 (2014-09-24)
Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adverse effects associated with
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