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Merck
CN

S2100000

磺胺甲噁唑

European Pharmacopoeia (EP) Reference Standard

别名:

4-氨基- N -(5-甲基-3-异恶唑基)苯磺酰胺, N 1 -(5-甲基异恶唑-3-基)磺胺

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关于此项目

经验公式(希尔记法):
C10H11N3O3S
化学文摘社编号:
分子量:
253.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6732984
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产品名称

磺胺甲噁唑, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

SMILES string

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

sulfamethoxazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Sulfamethoxazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 2


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alejandro Hoberman et al.
The New England journal of medicine, 370(25), 2367-2376 (2014-05-06)
Children with febrile urinary tract infection commonly have vesicoureteral reflux. Because trial results have been limited and inconsistent, the use of antimicrobial prophylaxis to prevent recurrences in children with reflux remains controversial. In this 2-year, multisite, randomized, placebo-controlled trial involving
Trimethoprim-sulfamethoxazole-associated aseptic meningitis: case reports and review of the literature.
A M Joffe et al.
The American journal of medicine, 87(3), 332-338 (1989-09-01)
P G Spitzer et al.
Reviews of infectious diseases, 8(3), 427-430 (1986-05-01)
A 55-year-old female recipient of an orthotopic liver transplant, who was receiving azathioprine, prednisone and cyclosporin, developed bacteremia due to Listeria monocytogenes. Because of a penicillin allergy, the patient was treated primarIly with trimethoprim-sulfamethoxazole, to which she responded well. The
D H Lawson et al.
Reviews of infectious diseases, 4(2), 429-433 (1982-03-01)
A comprehensive review is presented of the world literature on adverse reactions to trimethoprim-sulfamethoxazole (TMP-SMZ) since its first use in 1968, when concern was expressed about possible hematologic toxicity. Serious toxicity is a rare event, but when it occurs severe
Jih-Tay Hsu et al.
Journal of hazardous materials, 277, 34-43 (2014-03-19)
Antibiotics are commonly used in swine feed to treat and prevent disease, as well as to promote growth. Antibiotics released into the environment via wastewater could accelerate the emergence of antibiotic-resistant bacteria and resistance genes in the surrounding environment. In

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