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经验公式（希尔记法）:
C19H18N4O2
化学文摘社编号:
分子量:
334.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
Pimobendan for system suitability, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
SMILES string
CC(C(C1=CC=C(NC(C2=CC=C(OC)C=C2)=N3)C3=C1)=NN4)CC4=O
InChI key
GLBJJMFZWDBELO-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
pimobendan
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Pimobendan for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical mitral valve disease.
Adrian Boswood et al.
The Veterinary record, 168(8), 222-222 (2011-04-16)
[Calcium mobilizers and calcium sensitizers].
Masashi Arai
Nihon rinsho. Japanese journal of clinical medicine, 69 Suppl 9, 417-422 (2012-06-26)
Andrea C Lantis et al.
American journal of veterinary research, 72(12), 1646-1651 (2011-12-01)
To evaluate the effect of administration of the labeled dosage of pimobendan to dogs with furosemide-induced activation of the renin-angiotensin-aldosterone system (RAAS). 12 healthy hound-type dogs. Dogs were allocated into 2 groups (6 dogs/group). One group received furosemide (2 mg/kg
K Norton et al.
Journal of pharmacological and toxicological methods, 60(2), 193-197 (2009-06-16)
The ICH S7A and S7B guidelines require that effects of test substances on the cardiovascular system be assessed with respect to blood pressure, heart rate and electrocardiogram intervals. Where adverse effects are identified additional supplemental studies, including ventricular contractility, should
Domenico Caivano et al.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 14(3), 431-444 (2012-08-14)
Interventional cardiac procedures are traditionally performed using fluoroscopy, or, more recently, transesophageal echocardiography (TEE). Neither modality is widely available to practicing cardiologists worldwide. We examined whether balloon valvuloplasty of pulmonic stenosis (PS) and transarterial occlusion of patent ductus arteriosus (PDA)
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