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Y0000440

去羟肌苷

Name: 去羟肌苷
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

地丹诺辛, ddI, ddIno

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₂N₄O₃

化学文摘社编号:

69655-05-6

分子量:

236.23

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329830957

MDL number:

MFCD00077728

Beilstein/REAXYS Number:

3619529

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属性

grade

pharmaceutical primary standard

API family

didanosine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

InChI key

BXZVVICBKDXVGW-NKWVEPMBSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Didanosine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Overview of the preclinical development of an antiretroviral drug, 2',3'-dideoxyinosine.

J J McGowan et al.

Reviews of infectious diseases, 12 Suppl 5, S513-S520 (1990-07-01)

AIDS has remained a significant and worsening medical problem since its first description as a new clinical entity in 1981. In the past 6 years, substantial progress has been made in the chemotherapy for this disease; such progress is likely

Tenofovir and didanosine: a dangerous liaison.

Laura Waters et al.

The AIDS reader, 15(8), 403-406 (2005-08-23)

Tenofovir plus didanosine as Nrti backbone in HIV-infected subjects.

Marco Bongiovanni et al.

Current medicinal chemistry, 13(23), 2789-2793 (2006-11-01)

Nucleoside reverse transcriptase inhibitors (NRTI) are essential components of highly active antiretroviral treatment (HAART). Although several combinations can be used as NRTI backbones, not all are associated with good virological and/or immunological results. In particular, some NRTI combinations should be

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货号	GTIN
Y0000440	04061837568565