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经验公式（希尔记法）:
C21H18ClNO6
化学文摘社编号:
分子量:
415.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
阿西美辛, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)
SMILES string
COc1ccc2n(c(C)c(CC(=O)OCC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
InChI key
FSQKKOOTNAMONP-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
acemetacin
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
human ... PTGS1(5742), PTGS2(5743)
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Biochem/physiol Actions
该非甾体抗炎药 (NSAID) 专门增强蒽环类药（阿霉素、柔红霉素和 epirubium）的细胞毒性。避免 MRP 介导的多药耐药性。
Application
Acemetacin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
R Andrew Moore et al.
The Cochrane database of systematic reviews, (3)(3), CD007589-CD007589 (2009-07-10)
Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease and other musculoskeletal disorders in the UK, and widely available in other countries worldwide. This review sought to evaluate the efficacy and safety of oral acemetacin in
[Clinical profile of acemetacin].
H Rechziegler et al.
Medizinische Klinik (Munich, Germany : 1983), 85(5), 340-346 (1990-05-15)
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