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关于此项目
经验公式（希尔记法）:
C16H21NO3
化学文摘社编号:
分子量:
275.34
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
InChI
1S/C16H21NO3/c18-10-15(11-4-2-1-3-5-11)16(19)20-14-8-12-6-7-13(9-14)17-12/h1-5,12-15,17-18H,6-10H2
SMILES string
O=C(C(CO)C1=CC=CC=C1)O[C@@H]2C[C@@H]3CC[C@@H](N3)C2
InChI key
ATKYNAZQGVYHIB-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
atropine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Atropine impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Preparation of noratropine by oxidative n-demethylation of atropine.
M J Van der Meer et al.
The Journal of pharmacy and pharmacology, 35(6), 408-408 (1983-06-01)
Mohamad Houssam Al Balkhi et al.
Phytochemistry, 74, 105-114 (2011-11-16)
The presence of two compounds, norlittorine and norhyoscyamine, has been reported in leaves and roots of Datura innoxia; however their metabolic origin in the tropane alkaloid pathway has remained unknown. Precise knowledge of this pathway is a necessary pre-requisite to
M J Van der Meer et al.
The Journal of pharmacy and pharmacology, 38(10), 781-784 (1986-10-01)
A metabolic pattern of atropine in man, based on the detection of radiolabelled products in urine by high performance liquid chromatography after administration of [3H]atropine sulphate to a normal volunteer is proposed. Noratropine (24%), atropine-N-oxide (equatorial isomer) (15%), tropine (2%)
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