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经验公式（希尔记法）:
C17H23NO3
化学文摘社编号:
分子量:
289.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-104-8
Beilstein/REAXYS Number:
91260
MDL number:
InChI key
RKUNBYITZUJHSG-SPUOUPEWSA-N
InChI
1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
SMILES string
CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
grade
pharmaceutical primary standard
API family
atropine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Atropine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
D Poldermans et al.
European heart journal, 18 Suppl D, D86-D96 (1997-06-01)
Cardiac events in the peri-operative phase and late after non-cardiac vascular surgery are a major cause of morbidity and mortality. Numerous tests and diagnostic strategies--usually consisting of a combination of analysis of clinical risk factors and additional non-exercise dependent stress
Incidence, pathophysiology, and treatment of complications during dobutamine-atropine stress echocardiography.
Marcel L Geleijnse et al.
Circulation, 121(15), 1756-1767 (2010-04-21)
Peter Jones et al.
Archives of disease in childhood, 97(2), 139-144 (2011-05-31)
Bradycardia occurs during the intubation of some critically ill children as a result of vagal stimulation due to hypoxia and/or laryngeal stimulation; such 'stable' bradycardia is accompanied by selective vasoconstriction. Some induction drugs also induce bradycardia which may be accompanied
Kevan A C Martin et al.
Nature communications, 5, 5252-5252 (2014-10-25)
The axons of pyramidal neurons in the superficial layers of the neocortex of higher mammals form lateral networks of discrete clusters of synaptic boutons. In primary visual cortex the clusters are reported to link domains that share the same orientation
Joanna Kur et al.
The Journal of physiology, 592(3), 491-504 (2013-11-28)
Purinergic control of vascular tone in the CNS has been largely unexplored. This study examines the contribution of endogenous extracellular ATP, acting on vascular smooth muscle cells, in controlling vascular tone in the in vivo rat retina. Retinal vessels were
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