Merck
CN

Y0001344

三氯蔗糖

European Pharmacopoeia (EP) Reference Standard

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别名:
1,6-二氯-1,6-二脱氧 - β-D呋喃果糖基-4-氯-4-脱氧 - α-D-吡喃半乳糖苷, E955, 三氯蔗糖
Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS号:
分子量:
397.63
Beilstein:
3654410
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API family

sucralose

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

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此商品
1623626PHR134290984
Sucralose European Pharmacopoeia (EP) Reference Standard

Y0001344

三氯蔗糖

Sucralose United States Pharmacopeia (USP) Reference Standard

USP

1623626

三氯蔗糖

Sucralose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1342

三氯蔗糖

Sucralose analytical standard

Supelco

90984

三氯蔗糖

manufacturer/tradename

EDQM

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

format

neat

format

neat

format

neat

API family

sucralose

API family

sucralose

API family

sucralose

API family

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Sucralose EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

一种人类可以检测到的合成甜味剂。可激活肠内分泌细胞上的 T1R2/T1R3 甜味受体,引起胰高血糖素样肽-1 和葡萄糖依赖性胰岛素肽的激素分泌增加。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Susan S Schiffman et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 16(7), 399-451 (2013-11-14)
Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. In rats, sucralose ingestion
I Knight
Canadian journal of physiology and pharmacology, 72(4), 435-439 (1994-04-01)
Sucralose is a new sweetener discovered during a collaborative research program between Tate & Lyle and Queen Elizabeth College of the University of London. It is made by selective substitution of sucrose hydroxyl groups by chlorine, resulting in a highly
V Lee Grotz et al.
Regulatory toxicology and pharmacology : RTP, 55(1), 1-5 (2009-05-26)
Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is the non-nutritive sweetener in retail SPLENDA Sweetening Products, composed of sucralose and common food ingredients. A review of the extensive body of evidence that
Knut Erik Tollefsen et al.
The Science of the total environment, 438, 510-516 (2012-10-04)
Sucralose (1,6-dichloro-1,6-dideoxy-b-D-fructo-furanosyl 4-chloro-4-deoxy-a-D-galactopyranoside), sold under the trade name Splenda, has been detected in municipal effluents and surface waters in the United States and Europe. The environmental presence of sucralose has led to interest in the possibility of toxic effects in
Sucralose--an overview of the toxicity data.
H C Grice et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38 Suppl 2, S1-S6 (2000-07-07)

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