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Merck
CN

Y0001453

盐酸度洛西汀 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

(S)-度洛西汀 盐酸盐, (γS)-N-甲基-3-(萘-1-基氧)-3-(噻吩-2-基)丙烷-1-胺 盐酸盐, (+)-(S)-N-甲基-γ-(1-萘氧基)-2-噻吩丙胺 盐酸盐, (+)-N-甲基-3-(1-萘氧基)-3-(2-噻吩)-丙胺 盐酸盐, LY-248686 盐酸盐

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关于此项目

经验公式（希尔记法）:
C18H19NOS · HCl
化学文摘社编号:
136434-34-9
分子量:
333.88
NACRES:
NA.24
PubChem Substance ID:
329831430
UNSPSC Code:
41116107
MDL number:
MFCD06407958

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产品名称

盐酸度洛西汀 盐酸盐, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1

SMILES string

Cl.CNCC[C@H](Oc1cccc2ccccc12)c3cccs3

InChI key

BFFSMCNJSOPUAY-LMOVPXPDSA-N

grade

pharmaceutical primary standard

API family

duloxetine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... SLC6A2(6530), SLC6A4(6532)

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相关类别

Biochem/physiol Actions

盐酸度洛西汀是一种双重血清素/去甲肾上腺素再摄取抑制剂（SNRI），在临床上被广泛用作抗抑郁药和抗焦虑药。
盐酸度洛西汀是一种双重血清素/去甲肾上腺素再摄取抑制剂（SNRI）；抗抑郁药；抗焦虑药。

Application

Duloxetine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Laura M Fiori et al.
Translational psychiatry, 11(1), 439-439 (2021-08-23)
Identifying biomarkers of antidepressant response may advance personalized treatment of major depressive disorder (MDD). We aimed to identify longitudinal changes in gene expression associated with response to antidepressants in a sample of MDD patients treated with escitalopram. Patients (N = 153) from

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