O5500
四氧化锇
Sealed ampule.
别名:
“锇酸", 氧化锇(VIII)
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关于此项目
线性分子式:
OsO4
化学文摘社编号:
分子量:
254.23
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
244-058-7
MDL number:
Form:
powder
vapor density
8.8 (vs air)
Quality Level
vapor pressure
7 mmHg ( 20 °C)
form
powder
reaction suitability
reagent type: oxidant
bp
130 °C (lit.)
mp
39.5-41 °C (lit.)
SMILES string
O=[Os](=O)(=O)=O
InChI
1S/4O.Os
InChI key
VUVGYHUDAICLFK-UHFFFAOYSA-N
General description
四氧化锇(OsO4)是四面体构型的对称分子，含有第三过渡系过渡金属锇。四氧化锇可作为电镜的染料和非凝固型固定剂，主要用于组织病理学实验室中的生物组织检测。标本用四氧化锇再固定(postfix)可确保脂质保存。
Application
四氧化锇已作为固定剂用于短杆菌Brevibacterium mcbrellneri处理，以及经姜黄素处理的人癌细胞系的扫描电镜观察。还可作为固定剂用于弓形虫Toxoplasma gondii骨骼肌的超微结构分析。
Biochem/physiol Actions
四氧化锇化学性结合脂质，使其不溶；固定后仅余7%的脂质可提取。因此，用四氧化锇固定后，由磷脂组成的细胞膜会变黑且电子密度提高。它还可在石蜡处理过程中固定切片中的少量脂肪。
Other Notes
由于四氧化锇的危害性，建议在使用该化学品时使用安瓿开启器。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
此项目有
Manuel Marx et al.
Nature protocols, 7(2), 394-407 (2012-02-04)
In this report, we describe a reliable protocol for biocytin labeling of neuronal tissue and diaminobenzidine (DAB)-based processing of brain slices. We describe how to embed tissues in different media and how to subsequently histochemically label the tissues for light
Yukihiko Sugita et al.
The Journal of general virology, 92(Pt 11), 2485-2493 (2011-07-29)
Negatively stained influenza virions sometimes show irregular morphology and are often referred to as pleomorphic. However, this irregular morphology has not been visualized when ultrathin-section transmission and scanning electron microscopies are used. This study focused on the effects of ultracentrifugation
F Wyss et al.
Veterinary pathology, 52(6), 1235-1242 (2015-01-27)
Pododermatitis is frequent in captive flamingos worldwide, but little is known about the associated histopathologic lesions. Involvement of a papillomavirus or herpesvirus has been suspected. Histopathologic evaluation and viral assessment of biopsies from 19 live and 10 dead captive greater
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| O5500-10X1G | 04061833652909 |
| O5500-1G | 04061834235750 |
| O5500-5G-A | 04061834247975 |
| O5500-250MG | 04061834235774 |
| O5500-250G-A | 04061835517329 |
| O5500-100G-A | 04061837381171 |