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Merck
CN

P9776

Sigma-Aldrich

黄体酮

Sigma Reference Standard

别名:

4-孕烯-3,20-二酮

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关于此项目

经验公式（希尔记法）:
C21H30O2
化学文摘社编号:
57-83-0
分子量:
314.46
Beilstein:
1915950
EC 号:
200-350-6
MDL编号:
MFCD00003658
UNSPSC代码:
12352200
PubChem化学物质编号:
24899064

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包装

vial of 250 mg

mp

128-132 °C (lit.)

SMILES字符串

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

基因信息

human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208), Nr3c1(24413), Pgr(25154)

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生化/生理作用

诱导子宫内皮细胞的成熟和分泌活性；抑制排卵。
诱导子宫内皮细胞的成熟和分泌活性；抑制排卵。 孕激素与乳腺癌发病有关。

包装

Supplied in amber screw-cap vials

其他说明

黄体分泌的类固醇激素。

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H351,H360FD,H362

危险分类

Carc. 2 - Lact. - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
115K88171
115K8817

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K L Bruner-Tran et al.
Minerva ginecologica, 65(2), 199-213 (2013-04-20)
Progesterone action normally mediates the balance between anti-inflammatory and proinflammatory processes throughout the female reproductive tract. However, in women with endometriosis, endometrial progesterone resistance, characterized by alterations in progesterone responsive gene and protein expression, is now considered a central element
J H Check et al.
Clinical and experimental obstetrics & gynecology, 40(1), 37-39 (2013-06-04)
To determine if pregnancy rates following embryo transfer are reduced if the endometrial echo pattern in the late proliferative phase is isoechogenic (IE) vs triple line (TL). Pregnancy and implantation rates were compared according to TL vs IE pattern in
Long-term outcome for two heifers with a granulosa-theca cell tumour.
H Dobson et al.
The Veterinary record, 172(22), 581-581 (2013-05-03)
Huatao Chen et al.
American journal of physiology. Cell physiology, 304(12), C1131-C1140 (2013-04-19)
Ovarian circadian oscillators have been implicated in the reproductive processes of mammals. However, there are few reports regarding the detection of ovarian clock-controlled genes (CCGs). The present study was designed to unravel the mechanisms through which CCG ovarian circadian oscillators
S H Bao et al.
Clinical and experimental immunology, 172(3), 437-443 (2013-04-23)
Wnt pathways play an important role in pre-implantation embryo development, blastocyst implantation, and post-implantation uterine decidualisation. However, little is known about the potential role that Wnt signaling plays in patients with unexplained recurrent spontaneous miscarriage (URSM), and no single biomarker
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