1001502
USP
乙酰丙嗪 马来酸盐
United States Pharmacopeia (USP) Reference Standard
别名:
2-乙酰基-10-(3-二甲基氨基丙基)吩噻嗪 马来酸盐, 乙酰丙嗪 马来酸盐
等级
pharmaceutical primary standard
API类
acepromazine
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
OC(=O)\C=C/C(O)=O.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O
InChI
1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
FQRHOOHLUYHMGG-BTJKTKAUSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Acepromazine maleate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Acepromazine Maleate Injection
- Acepromazine Maleate Tablets
生化/生理作用
乙酰丙嗪是一种吩噻嗪类抗精神病药,仅用作兽药(马、狗和猫)。该化合物是抗精神病药物氯丙嗪(#C8138)的类似物。该药物被认为可以阻断大脑中的多巴胺受体。最近发现该化合物抑制 ABCG2 转运蛋白,该蛋白在肿瘤中的过表达与耐药性有关。
非典型抗精神病药。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
警示用语:
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral - STOT SE 3
靶器官
Central nervous system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Samer M Jaber et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 53(6), 684-691 (2015-02-05)
Extending a surgical plane of anesthesia in mice by using injectable anesthetics typically is accomplished by repeat-bolus dosing. We compared the safety and efficacy of redosing protocols administered either during an anesthetic surgical plane (maintaining a continuous surgical plane, CSP)
Elizabeth A Nunamaker et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 53(5), 494-501 (2014-09-26)
The goal of the current study was to compare the efficacy, adverse effects, and plasma buprenorphine concentrations of sustained-release buprenorphine (SRB) and buprenorphine after subcutaneous administration in dogs undergoing ovariohysterectomy. In a prospective, randomized, blinded design, 20 healthy adult female
Cathryn M Kolka et al.
Metabolism: clinical and experimental, 64(2), 330-337 (2014-12-04)
Insulin injected directly into skeletal muscle diffuses rapidly through the interstitial space to cause glucose uptake, but this is blocked in insulin resistance. As glucotoxicity is associated with endothelial dysfunction, the observed hyperglycemia in diet-induced obese dogs may inhibit insulin
Amadeu Gavaldà et al.
Pulmonary pharmacology & therapeutics, 28(2), 114-121 (2014-06-15)
This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators. All four antagonists had high affinity for the five muscarinic receptor sub-types (M1-M5);
Jinmei Wei et al.
Journal of the science of food and agriculture, 95(3), 598-606 (2014-06-21)
The use of xenobiotic compounds in animal husbandry has given rise to consumer anxieties regarding residual risk and food safety. Thus, animal tissues have become main samples for residue analysis and food safety for sedatives. In this study, a rapid
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