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Merck
CN

1068004

USP

Betamethasone sodium phosphate

United States Pharmacopeia (USP) Reference Standard

别名:

Betamethasone 21-phosphate disodium

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关于此项目

经验公式（希尔记法）:
C22H28FNa2O8P
化学文摘社编号:
151-73-5
分子量:
516.40
MDL编号:
MFCD00200361
UNSPSC代码:
41116107
PubChem化学物质编号:
329749107
NACRES:
NA.24

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等级

pharmaceutical primary standard

API类

betamethasone

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O

InChI

1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

InChI key

PLCQGRYPOISRTQ-LWCNAHDDSA-L

基因信息

human ... NR3C1(2908)

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相关类别

一般描述

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Betamethasone sodium phosphate Related Compound reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard and system suitability solution during the assay and identification by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP):
  • Dexamethasone Sodium Phosphate
  • Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension
  • Betamethasone Sodium Phosphate
  • Betamethasone Sodium Phosphate Injection

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险声明

H302,H360FD,H373

危险分类

Acute Tox. 4 Oral - Repr. 1B - STOT RE 2

靶器官

Liver,Kidney,Endocrine system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品
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分析证书(COA)

Lot/Batch Number

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Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5), 551-551 (2018)
Betamethasone Sodium Phosphate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 30(4), 549-549 (2020)
Dexamethasone Sodium Phosphate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(4), 1292-1292 (2020)
Betamethasone Sodium Phosphate Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 551-551 (2018)
Betamethasone sodium phosphate.
Nursing times, 100(49), 43-43 (2005-01-06)

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