产品名称
17α-Dihydroequilin, United States Pharmacopeia (USP) Reference Standard
SMILES string
OC1C2(C(CC1)C3=CCc4c(ccc(c4)O)C3CC2)C
InChI
1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3
InChI key
NLLMJANWPUQQTA-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
equilin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
17α-Dihydroequilin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Conjugated Estrogens
- Conjugated Estrogens Tablets
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
B R Bhavnani et al.
Journal of the Society for Gynecologic Investigation, 7(3), 175-183 (2000-06-24)
To compare the pharmacokinetics and relative bioavailabilities of key estrogen components of Premarin (Wyeth-Ayerst, Canada) with those of a generic conjugated estrogen preparation, C.E.S. (synthetic mixture of estrogens; ICN, Montreal, Canada) in healthy postmenopausal women. We conducted a randomized, single-dose
B R Bhavnani et al.
The Journal of clinical endocrinology and metabolism, 77(5), 1269-1274 (1993-11-01)
The constant infusion of [3H]equilin sulfate ([3H]EqS) was used to estimate the MCR of equilin sulfate (EqS) and to measure the conversion of this estrogen to equilin (Eq), equilenin (Eqn), equilenin sulfate (EqnS), 17 beta-dihydroequilin (17 beta-Eq), 17 beta-dihydroequilin sulfate
J G Wilcox et al.
Fertility and sterility, 66(5), 748-752 (1996-11-01)
To determine the independent biologic effects of 17 alpha-dihydroequilin sulfate. Prospective randomized study. University of Southern California Medical Center. Twenty-one postmenopausal women, mean age 50 +/- 2 (+/-SEM) years, and mean body mass index 27 +/- 2. Women were randomized
S A Washburn et al.
American journal of obstetrics and gynecology, 169(2 Pt 1), 251-254 (1993-08-01)
Our purpose was to determine the effect of Premarin (conjugated estrogens) and three of its component estrogens on uterine weight and plasma cholesterol concentrations in surgically menopausal female rats. A randomized trial of Premarin and three component estrogens--estrone sulfate, 17
Bhagu R Bhavnani et al.
Journal of the Society for Gynecologic Investigation, 9(2), 102-110 (2002-10-26)
In the present study, the constant infusion of [3H]17 beta-dihydroequilin sulfate ([3H]17 beta-EqS) was used to estimate the metabolic clearance rate (MCR) of 17 beta-dihydroequilin sulfate (17 beta-EqS) and to measure the conversion of this estrogen to equilin sulfate (EqS)
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