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Merck
CN

1235300

USP

依那普利 马来酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

( S )-N-[1-(乙氧基羰基)-3-苯基丙基]-Ala-Pro 马来酸盐

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关于此项目

经验公式(希尔记法):
C20H28N2O5 · C4H4O4
CAS Number:
分子量:
492.52
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

enalapril

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

C[C@@H](C(N1[C@H](C(O)=O)CCC1)=O)N[C@H](CC(OCC)=O)CCC2=CC=CC=C2.O=C(OO)/C=C\C(O)=O

InChI

1S/C21H30N2O5.C4H4O5/c1-3-28-19(24)14-17(12-11-16-8-5-4-6-9-16)22-15(2)20(25)23-13-7-10-18(23)21(26)27;5-3(6)1-2-4(7)9-8/h4-6,8-9,15,17-18,22H,3,7,10-14H2,1-2H3,(H,26,27);1-2,8H,(H,5,6)/b;2-1-/t15-,17-,18-;/m0./s1

InChI key

UQKQUZOIQFOJOI-KJHLASMFSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Enalapril maleate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Enalapril Maleate Tablets
  • Enalapril Maleate and Hydrochlorothiazide Tablets
  • Enalapril Maleate Compounded Oral Suspension
  • Enalaprilat Injection

生化/生理作用

一种长效血管紧张素转换酶抑制剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marta de Diego et al.
Journal of chromatographic science, 52(10), 1193-1197 (2013-12-04)
A simple and rapid stability-indicating liquid chromatographic method was developed and validated for the simultaneous determination of lisinopril and hydrochlorotiazide (HCTZ) in drug substances and dosage forms in the presence of degradation products. Forced degradation studies were conducted on the
Jorge Luiz Alves-Pereira et al.
The Journal of urology, 192(6), 1878-1883 (2014-06-01)
We evaluated whether antihypertensive drugs that act through the renin-angiotensin system would affect testis function. Ten mice were fed standard chow and 40 received a high energy density diet. At 8 weeks the high energy density diet mice were divided
A Uzawa et al.
Clinical and experimental immunology, 178(2), 245-252 (2014-07-06)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Bradykinin is the end-product of the kallikrein/kinin system, which has been recognized as an endogenous target for combating CNS inflammation. Angiotensin-converting enzyme (ACE) inhibitors influence the
Bjoern B Burckhardt et al.
Biomedical chromatography : BMC, 28(12), 1679-1691 (2014-05-03)
The benefit-risk ratio of combined blocking by the direct renin inhibitor aliskiren and an angiotensin-converting enzyme inhibitor (e.g. enalapril) on the renin-angiotensin-aldosterone system is discussed. No method was available for simultaneous determination of both drugs in urine. A novel sensitive
[Heart failure and LCZ696].
Guy Sabourin
Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec, 12(1), 61-61 (2015-02-06)

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