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Merck
CN

1287303

USP

加巴喷丁

United States Pharmacopeia (USP) Reference Standard

别名:

1-（氨甲基）-环己烷乙酸, 加巴喷丁

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关于此项目

经验公式（希尔记法）:
C9H17NO2
化学文摘社编号:
60142-96-3
分子量:
171.24
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749919
MDL number:
MFCD00865286
Beilstein/REAXYS Number:
2359739

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产品名称

加巴喷丁, United States Pharmacopeia (USP) Reference Standard

InChI key

UGJMXCAKCUNAIE-UHFFFAOYSA-N

SMILES string

NCC1(CC(O)=O)CCCCC1

InChI

1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)

grade

pharmaceutical primary standard

API family

gabapentin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... CACNA1A(773), CACNA1B(774), CACNA1C(775), CACNA1D(776), CACNA1E(777), CACNA1F(778), CACNA1G(8913), CACNA1H(8912), CACNA1I(8911), CACNA1S(779), CACNA2D1(781), CACNA2D2(9254), CACNA2D3(55799), CACNA2D4(93589), CACNB1(782), CACNB2(783), CACNB3(784), CACNB4(785), CACNG1(786), CACNG2(10369), CACNG3(10368), CACNG4(27092), CACNG5(27091), CACNG6(59285), CACNG7(59284), CACNG8(59283)

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相关类别

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Gabapentin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Gabapentin Capsules
  • Gabapentin Tablets
  • Gabapentin Compounded Cream
  • Gabapentin Compounded Oral Suspension

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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ESTIMATION OF GABAPENTIN IN HUMAN PLASMA USING LC-MS/MS METHOD.
Das, Binaya.
Asian Journal of Pharmaceutical and Clinical Research, 6.3, 213-216 (2013)
N S Gee et al.
The Journal of biological chemistry, 271(10), 5768-5776 (1996-03-08)
Gabapentin (1-(aminomethyl)cyclohexane acetic acid; Neurontin) is a novel anticonvulsant drug, with a mechanism of action apparently dissimilar to that of other antiepileptic agents. We report here the isolation and characterization of a [3H]gabapentin-binding protein from pig cerebral cortex membranes. The
Charles E Argoff et al.
Expert opinion on drug delivery, 9(9), 1147-1160 (2012-07-20)
Gabapentin immediate-release formulations (G-IR) administered three times a day is an efficacious treatment for postherpetic neuralgia (PHN), but its potential benefits may not be fully realized due to tolerability issues as well as its pharmacokinetic (PK) properties such as its
Lin Yu et al.
Spine, 38(22), 1947-1952 (2013-08-08)
Systematic review and meta-analysis. To review the literature systematically and make a comprehensive understanding of the efficacy of these 2 drugs in the management of postoperative pain after lumbar spinal surgery. Several trials that evaluated the efficacy of gabapentin and
Sarah Al-Bachari et al.
The Cochrane database of systematic reviews, 7(7), CD001415-CD001415 (2013-07-28)
The majority of people with epilepsy have a good prognosis and their seizures are well controlled by a single antiepileptic drug, but up to 30% develop drug-resistant epilepsy, especially those with partial seizures. In this review we summarise the current
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