产品名称
异烟肼, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
SMILES string
NNC(=O)c1ccncc1
InChI key
QRXWMOHMRWLFEY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
isoniazid
manufacturer/tradename
USP
mp
171-173 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Biochem/physiol Actions
针对结核菌的抗生素，抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性，在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Isoniazid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Isoniazid Tablets
- Isoniazid Injection
- Isoniazid Oral Solution
- Rifampin and Isoniazid Capsules
- Rifampin, Isoniazid, and Pyrazinamide Tablets
- Rifampin, Isoniazid, Pyrazinamide, and Ethambutol Hydrochloride Tablets
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
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