InChI key
CYDZMDOLVUBPNL-UHFFFAOYSA-N
SMILES string
CC(=O)OC1N=C(c2ccccc2Cl)c3cc(Cl)ccc3NC1=O
InChI
1S/C17H12Cl2N2O3/c1-9(22)24-17-16(23)20-14-7-6-10(18)8-12(14)15(21-17)11-4-2-3-5-13(11)19/h2-8,17H,1H3,(H,20,23)
grade
pharmaceutical primary standard
API family
lorazepam
manufacturer/tradename
USP
format
neat
drug control
kontrollierte Droge in Deutschland, regulated under CDSA - not available from Sigma-Aldrich Canada
application(s)
pharmaceutical (small molecule)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Lorazepam Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Lorazepam
- Lorazepam Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Legal Information
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Stationary ultrafiltration: a radio-tracer technique for studying stereoselective binding of racemic ligands.
M Simonyi et al.
Biochemical and biophysical research communications, 97(1), 1-7 (1980-11-17)
Application of ultrafiltration and CD spectroscopy for studying stereoselective binding of racemic ligands.
M Simonyi et al.
Biochemical and biophysical research communications, 109(3), 851-857 (1982-12-15)
K Liu et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(3), 609-613 (1991-05-01)
Rates of hydrolysis of racemic and enantiomeric lorazepam 3-acetates (LZA) by esterases in human and rat liver microsomes and rat brain S9 fraction were compared. LZA and its hydrolysis product were analyzed by chiral stationary phase HPLC. When rac-LZA was
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
R Brouns et al.
Acta neurologica Belgica, 102(1), 19-20 (2002-07-04)
Ilona Fitos et al.
Chirality, 14(5), 442-448 (2002-05-02)
Kinetic and equilibrium binding studies were performed on the interaction of warfarin enantiomers with human serum albumin (HSA) in the absence and presence of lorazepam acetate (LoAc) enantiomers. Binding kinetics were followed by recording changes in the fluorescence of warfarin
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