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1604803

USP

利托那韦

Name: 利托那韦
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

1,3-噻唑-5-基甲基 N-[（2S,3S,5S）-3-羟基-5-[[（2S）-3-甲基-2-[[甲基-[（2-丙-2-基-1,3-噻唑-4-基）甲基]氨基甲酰基]氨基]丁酰基]氨基]-1,6-二苯基己基-2-基]氨基甲酸酯

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关于此项目

经验公式（希尔记法）:

C₃₇H₄₈N₆O₅S₂

化学文摘社编号:

155213-67-5

分子量:

720.94

MDL number:

MFCD08694944

UNSPSC Code:

41116107

NACRES:

NA.24

eCl@ss:

25140904

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属性

biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

ritonavir

form

powder

packaging

pkg of 200 mg

manufacturer/tradename

USP

storage condition

protect from light

color

white to tan

solubility

acetonitrile: slightly soluble, ethanol: freely soluble, methanol: freely soluble, methylene chloride: freely soluble, water: practically insoluble

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

SMILES string

[s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI key

NCDNCNXCDXHOMX-XGKFQTDJSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

Find answers to frequently asked questions on USP products in USP FAQs.

Application

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Ritonavir Capsules
Ritonavir Tablets
Ritonavir Oral Solution
Lopinavir and Ritonavir Tablets
Lopinavir and Ritonavir Oral Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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象形图

GHS07

警示词

Warning

危险代码

H302 + H312 + H332

预防性声明

P261 - P280 - P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

怎么回事？

WGK 3

闪点 (F)

Not applicable

闪点 (°C)