grade
pharmaceutical primary standard
agency
USP
API family
n-acetylneuraminic acid
form
powder
manufacturer/tradename
USP
application(s)
USP Biologics
pharmaceutical (small molecule)
format
neat
storage temp.
-65 to -96°C
SMILES string
N([C@H]1[C@@H](O[C@](C[C@@H]1O)(O)C(=O)O)[C@H](O)[C@H](O)CO)C(=O)C
InChI
1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
InChI key
SQVRNKJHWKZAKO-PFQGKNLYSA-N
General description
N-Acetylneuraminic acid (Neu5Ac) is the most abundant sialic acid found on the terminal positions of glycan chains in glycoproteins and glycolipids. It plays a critical role in cell signaling and pathogen recognition. The USP standard supports identification and quantitation in glycosylation analysis of biopharmaceuticals.
The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Application
也用于制备标准储备溶液，用于根据以下美国药典（USP）通则进行寡糖和唾液酸分析：
- 〈210〉 单糖分析
- 〈129〉 重组治疗性单克隆抗体的分析流程
Analysis Note
Other Notes
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable