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Merck
CN

1705006

USP

L-酪氨酸

United States Pharmacopeia (USP) Reference Standard

别名:

(S)-2-氨基-3-(4-羟苯基)丙酸, 3-(4-羟苯基)-L-丙氨酸

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关于此项目

线性分子式:
4-(HO)C6H4CH2CH(NH2)CO2H
化学文摘社编号:
60-18-4
分子量:
181.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751451
MDL number:
MFCD00002606
Beilstein/REAXYS Number:
392441

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产品名称

L-酪氨酸, United States Pharmacopeia (USP) Reference Standard

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

grade

pharmaceutical primary standard

API family

tyrosine

form

fine crystals

manufacturer/tradename

USP

mp

>300 °C (dec.) (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

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相关类别

Other Notes

多巴胺和其他儿茶酚胺的氨基酸前体
Sales restrictions may apply.
This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

ʟ-Tyrosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tyrosine
  • Glycyl-l-tyrosine
  • Levodopa
  • N-Acetyltyrosine
  • Hyaluronidase Injection

General description

ʟ-Tyrosine is a non-essential amino acid involved in the biosynthesis of catecholamines, thyroid hormones, and melanin. The USP ʟ-Tyrosine standard guarantees the purity and quality of this amino acid, supporting its use in peptide synthesis, cell culture media, and therapeutic development.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

存储类别

13 - Non Combustible Solids

wgk

WGK 1

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Andrzej Slominski et al.
Pigment cell & melanoma research, 25(1), 14-27 (2011-08-13)
There is evidence that L-tyrosine and L-dihydroxyphenylalanine (L-DOPA), besides serving as substrates and intermediates of melanogenesis, are also bioregulatory agents acting not only as inducers and positive regulators of melanogenesis but also as regulators of other cellular functions. These can
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion
Maria B Feeney et al.
Antioxidants & redox signaling, 17(11), 1571-1579 (2012-03-20)
The understanding of physiological and pathological processes involving protein oxidation, particularly under conditions of aging and oxidative stress, can be aided by proteomic identification of proteins that accumulate oxidative post-translational modifications only if these detected modifications are connected to functional
Vincent Dunet et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 53(2), 207-214 (2012-02-04)
For the past decade, PET with (18)F-fluoro-ethyl-tyrosine ((18)F-FET) has been used in the evaluation of patients with primary brain tumors (PBTs), but so far series have reported only a limited number of patients. The purpose of this systematic review and
Sharon L Bourke et al.
Advanced drug delivery reviews, 55(4), 447-466 (2003-04-23)
The natural amino acid L-tyrosine is a major nutrient having a phenolic hydroxyl group. This feature makes it possible to use derivatives of tyrosine dipeptide as a motif to generate diphenolic monomers, which are important building blocks for the design
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