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经验公式（希尔记法）:
C23H27N5O3
化学文摘社编号:
分子量:
421.49
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C23H27N5O3/c1-4-7-20(29)28(21(15(2)3)23(30)31)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)22-24-26-27-25-22/h5-6,8-13,15,21H,4,7,14H2,1-3H3,(H,30,31)(H,24,25,26,27)/t21-/m0/s1
SMILES string
CCCC(=O)N(Cc1ccc(cc1)-c2ccccc2-c3nnn[nH]3)[C@@H](C(C)C)C(O)=O
InChI key
OKAQHVJSXLGXET-NRFANRHFSA-N
grade
pharmaceutical primary standard
API family
valsartan
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
This USP reference standard is intended for use in specified quality tests and assays as specified in the USP compendia.
It is also used in the preparation of standard and system suitability solutions for the determination of organic impurities and performance tests of tablets and capsules, in accordance with the USP monographs, by liquid chromatography (LC) combined with UV detection, of the following:
In addition, it is used in the assay test of valsartan tablets by LC-UV following the USP monograph “Valsartan Tablets”.
It is also used in the preparation of standard and system suitability solutions for the determination of organic impurities and performance tests of tablets and capsules, in accordance with the USP monographs, by liquid chromatography (LC) combined with UV detection, of the following:
- Valsartan
- Amlodipine and valsartan tablets
- Valsartan and hydrochlorothiazide tablets
- Amlodipine, valsartan, and hydrochlorothiazide tablets
In addition, it is used in the assay test of valsartan tablets by LC-UV following the USP monograph “Valsartan Tablets”.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Valsartan Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 47(5), 4579-4579 (2017)
Valsartan and Hydrochlorothiazide Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 4580-4580 (2015)
Tablet formulation and development of a validated stability indicating hplc method for quantification of valsartan and hydrochlorthiazide combination.
Kharoaf, M. A. H. E. R., et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 4.3, 284-290 (2012)
Valsartan
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(3), 4577-4577 (2020)
Amlodipine and Valsartan Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(2), 275-275 (2017)
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