- Antioxidant and antibacterial studies of arylazopyrazoles and arylhydrazonopyrazolones containing coumarin moiety.
Antioxidant and antibacterial studies of arylazopyrazoles and arylhydrazonopyrazolones containing coumarin moiety.
European journal of medicinal chemistry (2009-08-04)
P Manojkumar, T K Ravi, S Gopalakrishnan
PMID19646797
摘要
A series of novel 1-(4-methylcoumarinyl-7-oxyacetyl)-3,5-dimethyl-4(arylazo)pyrazoles and 1-(4-methylcoumarinyl-7-oxyacetyl)-3-methyl-4-(substituted phenyl) hydrazono-2-pyrazolin-5-ones were synthesised and evaluated for antibacterial and antioxidant activities. Compounds 3b, 3g, 5b, 5d and 5g showed good antibacterial activity and compound 5e was found to be the most active antioxidant in the series, and thus represent a new class of promising lead compounds.
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Sigma-Aldrich
L -抗坏血酸, puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)